Disease modifying treatment available:
Time critical diagnosis and management:
Lateralising:
| Subclassifications | Epidemiology | Clinical features |
|---|---|---|
| Alpers-Huttenlocher syndrome | None | Bilateral ptosis Seizure Epilepsy Liver failure Developmental regression |
| Neurogenic Weakness, Ataxia and Retinitis Pigmentosa | None | Proximal muscle weakness Peripheral neuropathy Retinitis pigmentosa |
| Leber hereditary optic neuropathy | None | Optic neuropathy |
| Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke like episodes | None | |
| Leigh syndrome | None |