Generalized tonic-clonic seizure

Disease modifying treatment available:
Time critical diagnosis and management:
Lateralising:

Definition

None



Taxotomy

Aetiology

None

Supercategory
Generalized seizure
Disorder Clinical features Associated features Investigations Disease modifying treatment available Time critical
Myoclonic epilepsy with ragged-red fibers Epilepsy
Myoclonic seizure
Cerebellar ataxia
Dementia
Sensorineural hearing loss
Optic neuropathy
Atonic seizure
Absence seizure
Proximal muscle weakness
Short stature
Wolff-Parkinson-White syndrome


Clinical features


None

Generalized tonic-clonic seizure may cause the following:




Treatment


NICE Guidance 217 (April 2022) recommends offering sodium valproate first line to males, females aged 10 years or younger who are unlikely to need treatment until childbearing age and women who are unable to have children.

For women of childbearing age, NG 217 recommends offering lamotrigine or levetiracetam first line.




Research


Open questions

None